Spermosens AB (publ) INTERIM REPORT JANUARY - JUNE 2025

We achieved a pivotal milestone during the second quarter, as strong clinical results clearly confirmed the diagnostic value of JUNO-Checked.

JANUARY 1st – JUNE 30st 2025

SIGNIFICANT EVENTS DURING THE QUARTER

02-04-2025Spermosens reports positive second interim results from clinical study

07-05-2025Spermosens AB INTERIM REPORT JANUARY – MARCH 2025

15-05-2025NOTICE OF ANNUAL GENERAL MEETING 2025 IN SPERMOSENS AB

26-05-2025Spermosens publishes annual report for the financial year 2024

02-06-2025The subscription price for warrants of series TO 5 has been determined – the exercise period begins today

05-06-2025The capital raise and issue announced in March 2025 is approved by Inspectorate of Strategic Products

11-06-2025Spermosens concludes clinical study with statistically significant results supporting the diagnostic value of JUNO-Checked

13-06-2025Chairman and CEO of Spermosens exercise TO5 warrants

16-06-2025Spermosens AB Announces Results from Annual General Meeting on 16 June 2025

17-06-2025Spermosens announces outcome of exercise of warrants series TO 5

CEO’s COMMENTS

We achieved a pivotal milestone during the second quarter, as strong clinical results clearly confirmed the diagnostic value of JUNO-Checked. This outcome represents a major validation of our technology and significantly strengthens our ability to move the solution forward together with future partners.

The clinical study, conducted at the Reproductive Medicine Center in Malmö, showed a clear and statistically significant correlation between the JUNO Score — which measures sperm binding to the JUNO receptor of the egg — and fertilization rates in IVF. Notably, 22% of the men had a low JUNO Score despite normal sperm parameters. This underscores the limitations of conventional semen analysis and highlights the unique insights JUNO-Checked provides at a critical stage of fertilization.

The results show why JUNO-Checked could become a game changer in the infertility market. It has the potential to improve IVF outcomes, support better selection of sperm donors, and even help identify periods of peak fertility in men. With much infertility still unexplained and current methods limited, JUNO-Checked provides information that was previously unavailable — insights that can eventually bring real value to patients, clinicians and sperm banks.

The significance of this milestone is already reflected in our business development. The clinical validation has increased the interest from companies established Assisted Reproductive Technology (ART) market, strengthening our confidence as we advance our licensing and partnership strategy.

The TO5 warrants were fully exercised during the quarter. Together with strategic investments in the first quarter, we have the financial resources needed to execute our plans. This allows us to focus on developing the third-generation JUNO-Checked system, ensuring higher throughput, faster analysis, and smooth integration into routine laboratory practice.

I am fortunate to work alongside highly skilled and dedicated people whose expertise and stamina have been instrumental in reaching this milestone. My sincere thanks go to the Reproductive Medicine Center in Malmö, whose collaboration made this achievement possible. I also appreciate the commitment of our development partners and the confidence of our investors — all of which enable us to continue progressing toward a solution that may help many affected by infertility, while creating value for shareholders.

With JUNO-Checked now clinically validated, increasing interest from potential partners, and the resources to move forward, I feel confident in our chance to succeed. Our focus remains firmly on advancing JUNO-Checked toward the market.

Tore Duvold, CEO of Spermosens AB

20 August 2025

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